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Dr Carina Monico

Chemistry Research Laboratory, University of Oxford

Friday, May 9th, 2014 at 02:00:00 PM

Conference Room Querzoli LENS

Published on-line at 10:51:07 AM on Wednesday, May 7th, 2014

Engineering droplet interface bilayers for single-molecule membrane biology

Droplet interface bilayers (DIBs) are presented as a biomimetic model of cell membranes for investigating the behaviour of membrane proteins within their natura

Droplet interface bilayers (DIBs) are presented as a biomimetic model of cell membranes for investigating the behaviour of membrane proteins within their natural environment. DIBs are created when a nanolitre-sized aqueous droplet is brought into contact with a supporting hydrogel that is immersed in a lipid-in-oil solution. The benefits of using DIBs as cell membrane mimics in conjunction with single-molecule imaging techniques are discussed. It is anticipated that DIBs will ultimately lead to a better understanding of membrane and protein function, representing as well a novel tool for biotechnology.

For further informations, please contact Dr Marco Capitanio.